The name Karlene is a name traditionally for girls. The meaning of Karlene is 'womanly', 'strength', and 'feminine of Karl'. Also, in Latin it means 'little and womanly', and 'free woman'. The name has two syllables, and it is pronounced as kar-lene. The name is so popular that it has been used for characters in films, novels, and songs. Interestingly, there are notable persons with the name Karlene, like Karlene Faith who is a feminist writer, Karlene Maywald who is a politician in Australia, Karlene Haughton who is a hurdles athlete, and Karlene Crockett who is an actress who acted in the movie 'A Matter of Time'.