The meaning of Santiago is 'of Saint James' and the name is of Spanish origin. Another meaning is 'gift of God'. Typically, it is a popular first name for boys. The name is said to have been discovered in Galicia, a Christian kingdom in medieval Spain. The name has popularly appeared in many works of fiction. There was a character called Santiago in 'The Old Man And The Sea'. The name also featured in Paulo Coehlo’s most famous work, 'The Alchemist'. More recently, Amy Santiago is a Spanish-American character played by Melissa Fumero in 'Brooklyn Nine-Nine'. Santiago has also been used as a pen name, most notably by Elena Fernandez Gomez, who went by the name 'Elena Santiago'. Santiago is the capital city of Chile.